PRADEEP ALBERTThe journal
Emerging Therapies and Research
Dr. Albert’s writing on emerging therapies and research: what the evidence supports, and what still needs more study.
65 articles in Emerging Therapies and Research. Showing 49 to 65, page 3 of 3.
Emerging Therapies and Research ·
Unraveling the Mysteries of Mitochondria: From Energetics to Signaling Roles
The Genesis of Mitochondrial Research Modern mitochondrial research traces back to several pivotal discoveries in the 20th century. In 1937, German biochemist Hans Krebs outlined how mitochondria metabolize nutrients through the TCA cycle to generate energy carriers like NADH. In 1960, British biologist Peter Mitchell solved how mitochondria synthesize ATP through oxidative phosphorylation using the…
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Emerging Therapies and Research ·
Demystifying Scientific Studies: A Guide to Reading and Interpreting Medical Research
The Scientific Process and Types of Studies Before a scientific study even begins, researchers start by forming a hypothesis about a particular relationship between variables. From there, they design experiments to test that hypothesis, get approval from ethics committees, determine the number of human or animal subjects needed, outline key outcomes to measure, plan statistical…
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Emerging Therapies and Research ·
Unlocking the Genetic Secrets Behind Rare and Complex Diseases
The Rapid Pace of Advancement in Genetic Technologies It's astonishing to reflect on how quickly genetic testing technologies have advanced over a relatively short period of time. Just a few decades ago, identifying disease-causing genes was an arduous process that could take years. Now, thanks to innovations like high-throughput sequencing, we can sequence a person's…
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Emerging Therapies and Research ·
Ketamine: A Novel Antidepressant With Promise and Caution
The Origins and Effects of Ketamine Ketamine was originally synthesized in the 1960s as an anesthetic agent, valued for maintaining blood pressure and respiratory drive. However, clinicians soon noticed it could cause hallucinations and "out-of-body" sensations. While concerning, these psychedelic properties led researchers in the 2000s to explore ketamine as a rapid-acting antidepressant. In the…
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Emerging Therapies and Research ·
Hacking Metabolism: New Insights into Optimizing Cellular Health
The Frontiers of Metabolomics Research Metabolism refers to the complex network of chemical reactions that convert food into energy and synthesize essential molecules in our bodies. The relatively new field of "metabolomics" aims to measure all of the metabolites and metabolic pathways operating in a cell, tissue, or organism. Key topics in metabolomics include: Studying…
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Cancer ·
Leveraging Liquid Biopsies to Revolutionize Early Cancer Detection
The Devastating Impact of Late-Stage Cancer Detection Lung cancer is the number one cause of cancer death, taking more lives annually than breast, prostate, and colon cancers combined. Historically, the vast majority of lung cancer patients have faced a grim prognosis, with few treatment options once their disease has progressed or spread widely throughout the…
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Emerging Therapies and Research ·
Unraveling the Complex Biology of Obesity
The Brain's Critical Role in Regulating Body Weight Obesity has become a global public health crisis, with rates skyrocketing over the past few decades. While the condition is often blamed solely on poor lifestyle choices, the biological underpinnings of obesity are far more complex. Emerging research has highlighted the central role of the brain in…
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Cardiovascular Health ·
The Important Role of Lipoprotein(a) in Heart Health
What is Lipoprotein(a)? Lipoprotein(a), or LP(a), is a lipoprotein particle consisting of a low-density lipoprotein (LDL) particle bound to a protein called apolipoprotein(a). The levels of LP(a) are determined primarily by the liver's production rate of apolipoprotein(a). LP(a) Levels in the Population About 20% of people have elevated LP(a) levels, with higher rates seen in…
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Emerging Therapies and Research ·
Understanding the Causes, Diagnosis, and Treatments for Hair Loss
Hair Loss is Extremely Common Among Both Men and Women Hair loss is an extremely common issue affecting close to 100 million Americans. It can occur in both men and women due to a variety of factors including genetics, hormones, certain medications, and underlying health conditions. Male pattern baldness linked to dihydrotestosterone (DHT) accounts for…
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Emerging Therapies and Research ·
The Promise and Perils of Hormone Replacement Therapy for Women
A Long History of Mistreatment Led to Justified Skepticism Hormone replacement therapy (HRT) for women has a long and controversial history. In the 1940s and 1950s, estrogen was found to effectively relieve troublesome menopausal symptoms, which on average last 7-10 years, as well as reduce the risk of heart disease, the #1 killer of women.…
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Emerging Therapies and Research ·
New Hope for Fibromyalgia Patients: Examining the Potential of Specialized Pro-Resolving Mediators
Examining the Potential of Specialized Pro-Resolving Mediators Fibromyalgia is a perplexing condition characterized by widespread muscle pain, profound fatigue, sleep dysfunction and cognitive difficulties. It affects up to 6% of the general population and is much more prevalent in women. Despite decades of research, the underlying mechanisms behind fibromyalgia remain unclear. As a result, treatment…
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Emerging Therapies and Research ·
Regenerating Health: The Promising Potential of Stem Cell Treatments
An Introduction to Stem Cell Therapy Stem cells have emerged as a hugely promising option for regenerative medicine. Often derived from a patient's own fat tissue, these intrinsically versatile cells possess the ability to develop into whatever cell types are required to carry out repairs in the body. Early research tracking stem cells shows they…
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Emerging Therapies and Research ·
A Comprehensive Look at Hormone Health
Introducing the DUTCH Test Assessing hormone balance and detoxification pathways is an important part of functional and integrative medicine. The Dried Urine Test for Comprehensive Hormones (DUTCH) provides a detailed urinary analysis of key hormones and metabolites to help practitioners personalize treatment approaches. Rather than relying on serum, saliva, or 24-hour urine collection, the DUTCH…
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Emerging Therapies and Research ·
Understanding the Best Testing Mediums for Hormones
Introduction Hormone testing is an essential part of functional medicine practice. Being able to accurately assess a patient's hormone levels allows practitioners to identify imbalances and customize treatment plans. However, choosing the right testing medium – serum, urine, or saliva – is key to getting reliable results. The Limitations of Serum Testing Blood serum testing…
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Emerging Therapies and Research ·
Preventing Cognitive Decline and Alzheimer's Through Diet, Lifestyle, and Inflammation Control
The Brain Loves Ketones Research increasingly shows the benefits of ketogenic diets and ketone supplementation for providing the brain an efficient, "clean" fuel source to maintain optimal function. Studies demonstrate that inducing nutritional ketosis through high fat, low carb diets or supplements like MCT oil can significantly improve symptoms in neurological conditions like Alzheimer's and…
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Emerging Therapies and Research ·
Ensuring the Quality and Safety of Medicinal Mushroom Supplements
An Introduction to Medicinal Mushrooms Medicinal mushrooms have been used in traditional Chinese medicine for thousands of years. Unlike regular culinary mushrooms, medicinal varieties contain special compounds that can have therapeutic effects on health and disease. Some of the most well-studied medicinal mushrooms include reishi, shiitake, maitake and cordyceps. Medicinal mushrooms have a complex life…
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Emerging Therapies and Research ·
Unlocking the Secrets of Aging: Insights from Man's Best Friend
Understanding the Biology of Aging The process of aging intrigues scientists across disciplines, from biologists to gerontologists. To better understand the underlying biological mechanisms that drive aging, researchers have turned to an unlikely model organism – the domestic dog. As beloved family members, dogs share our homes and environments while also demonstrating substantial genetic diversity…
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